Nanoscale optical trap for fluorescent nanoparticles

Optical Trap Assisted Nanoscale Laser Direct-Write Patterning

Laser direct-write patterning methods are traditionally limited by the diffraction limit to size scales several hundreds of nanometers at the minimum. In this work, we demonstrate a new method of laser based patterning that overcomes these limitations by taking advantage of near-field enhancement at the surface of dielectric microspheres. Polystyrene microspheres are trapped in CW Bessel beam l...

Optical vortex trap for resonant confinement of metal nanoparticles.

The confinement and controlled movement of metal nanoparticles and nanorods is an emergent area within optical micromanipulation. In this letter we experimentally realise a novel trapping geometry near the plasmon resonance using an annular light field possessing a helical phasefront that confines the nanoparticle to the vortex core (dark) region. We interpret our data with a theoretical framew...

Nanoscale “fluorescent stone”: Luminescent Calcium Fluoride Nanoparticles as Theranostic Platforms

Calcium Fluoride (CaF2) based luminescent nanoparticles exhibit unique, outstanding luminescent properties, and represent promising candidates as nanoplatforms for theranostic applications. There is an urgent need to facilitate their further development and applications in diagnostics and therapeutics as a novel class of nanotools. Here, in this critical review, we outlined the recent significa...

Cancer optical imaging using fluorescent nanoparticles.

Bright fluorescent nanoparticles for developing potential optical imaging contrast agents.

Fluorescent cross-linked nanoparticles with variable fluorophore loading amounts, locations, and particle sizes were synthesized from sequential one-pot functionalization/cross-linking of block copolymer micelles with amine-terminated dye and cross-linker molecules, via reductive amination and amidation. The fluorescence quantum yield and brightness of these nanoparticles were evaluated by stea...